The Xbox 360 Media Remote does indeed function properly with Openelec with the below fix in an autostart script.
# modprobe -r nuvoton-cir
echo "auto" > /sys/bus/acpi/devices/NTN0530\:00/physical_node/resources
modprobe nuvoton-cir
HOWEVER.....
Once the NUC has been put to sleep, virtually everybody is unable to wake up the NUC with this remote! When pressing the physical power button on the unit, the NUC wakes up and the remote fully functions in XBMC, even switchuing the NUC off using the power button on the remote works.
Funny how the power button on the remote is capable of putting the NUC to sleep but that the same power button is unable to wake up the NUC.