Thanks for joining the NUC community.
I understand you have a RME Babyface device that is not working properly with NUC DC32171IYE.
This may be compatibility issue; however, there are couple of things to try before determining this problem is hardware compatibility.
1. Let's try updating the computer BIOS:
File name: GKPPT10H.86A.0050.EB.EXE
Before updating BIOS, please check list of fixes here: http://downloadmirror.intel.com/23946/eng/GK_0050_ReleaseNotes.pdf
2. Test RME Babyface on a different computer, different NUC model or even a laptop system.
If you are still having same problem, I recommend checking with RME forum community for any issues or some tips other customers may be able to provide.
Thanks
Allan.